Evidence-Based Clinical Insights
Academic articles, clinical research, and in-depth analysis of addiction psychiatry, naltrexone therapy, and circuit-based understanding of behavioral and substance-use disorders by Dr. Sidharth Sood.
This section features peer-reviewed quality academic articles authored by Dr. Sidharth Sood, DM Addiction Psychiatry (AIIMS Delhi). Each article combines rigorous clinical evidence with practical clinical implementation strategies.
Articles focus on addiction neuroscience, evidence-based pharmacotherapy, behavioral addictions, and transdiagnostic applications of addiction psychiatry concepts. All content integrates the latest research findings with Dr. Sood's 10+ years of clinical expertise.
These articles are designed for medical professionals, researchers, psychiatrists, and healthcare providers seeking comprehensive understanding of addiction mechanisms and treatment approaches grounded in neuroscience and clinical evidence.
A comprehensive exploration of naltrexone's mechanism, evidence base, and clinical applications across addiction and psychiatric disorders
Addiction psychiatry is undergoing a paradigm shift from symptom-based treatment to circuit-based understanding. Naltrexone exemplifies this evolution—a μ-opioid receptor antagonist that directly targets reward system dysregulation. This article examines naltrexone's neurobiological mechanism, synthesizes evidence from landmark RCTs and meta-analyses, addresses safety concerns (particularly hepatic), and explores transdiagnostic applications beyond addiction. Clinical pearls and implementation strategies are provided for practicing psychiatrists.
"Naltrexone is not just an anti-addiction drug—it is a reward circuit modulator with transdiagnostic potential. Understanding its mechanism enables clinicians to identify broader applications and optimize patient selection."
Author: Dr. Sidharth Sood, MBBS (MAMC), MD, DNB, DM Addiction Psychiatry (AIIMS)
Type: Peer-review quality clinical review article
Focus: Evidence-based practice, neuroscience translation, clinical decision-making
Target Audience: Psychiatrists, addiction specialists, medical professionals, academic researchers
Effectiveness of Theta Burst Stimulation on Craving and Alcohol Use among Inpatients with Alcohol Use Disorder
Original research conducted at AIIMS Delhi examining neuromodulation's role in addiction treatment. This thesis investigated non-pharmacological approaches to craving reduction in alcohol use disorder, contributing to the evidence base for brain stimulation therapies in addiction psychiatry.
Affiliation: National Drug Dependence Treatment Centre (NDDTC), AIIMS Delhi
CAMCON 1.0 - March 2026 (NIMHANS, Bangalore)
Key Symposiums: Leading expert talks on stimulant use disorders and the emerging role of psychedelics in psychiatric treatment. Presentations emphasize evidence-based approaches and neuroscientific understanding of these complex topics.
Clinical Relevance: Contributing to national-level conversations about addiction psychiatry, emerging treatments, and clinical decision-making frameworks for Indian practitioners.
Additional academic articles and clinical insights on addiction psychiatry and evidence-based treatment approaches.
Detailed examination of dopamine pathways, reward system dysregulation, and therapeutic interventions targeting these circuits
Comprehensive analysis of gambling, gaming, sexual behavior, and internet addictions from a psychiatric perspective
Strategies for managing co-occurring addiction and psychiatric conditions with emphasis on circuit-based treatment
Review of novel pharmacological and neuromodulation approaches and their clinical applications
These academic articles are designed for psychiatrists, addiction specialists, medical professionals, researchers, medical students, and healthcare providers seeking comprehensive, evidence-based understanding of addiction psychiatry and treatment approaches.
All articles maintain peer-review quality standards with extensive citations, integration of latest research, and clinical expertise. Each article incorporates evidence from landmark studies, meta-analyses, and contemporary research.
All academic content incorporates the latest published evidence through 2026. Articles are updated regularly as new research emerges, ensuring that clinical recommendations reflect current best evidence.
Yes. These articles are suitable for professional development, CME preparation, academic research, and clinical decision-making. They provide the evidence base for implementing evidence-based addiction psychiatry practices.
Dr. Sood holds a DM (Doctorate) in Addiction Psychiatry from AIIMS Delhi, MD in Psychiatry from IHBAS, DNB in Psychiatry, and MBBS from Maulana Azad Medical College. He is AIIMS-trained with research contributions to addiction neuroscience.
Full articles are available through this platform. Contact section or registration enables access to complete academic content, references, and supplementary materials.
Access comprehensive academic articles and research-backed insights from an AIIMS-trained addiction psychiatry expert.